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The World's First PICC That Combining the Strength of a Power-injectable
Polyurethane with the Biocompatibility and Ethanol Resistance of Silicone

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The only catheter on the market indicated for prolonged intraluminal exposure to compatible solutions containing up to 70% ethanol

  • Ethanol has been demonstrated by several studies to prevent or resolve Catheter-related Bloodstream Infections (CRBSI) in animal models and human studies.1 2 3 4

  • Several studies have demonstrated ethanol locks to be effective in preventing or clearing central line lipid occlusion due to total parenteral nutrition.5 6 7

  • The Piper PICC is made with Quadrasil™ Siliconized Polyurethane designed to deliver the mechanical and physical properties of polyurethane and the biocompatibility of silicone.

  • The silicone is bound to the polyurethane at the molecular level, making it permanent and noneluting for the life of the catheter.

  • Quadrasil™ technology is present throughout the catheter, including the outer surface, inner lumen, and the tip.

  • The Piper PICC does not contain antibiotics, antimicrobials, or heparin




Lower Rates of Thrombus Formation

In-vitro blood loop model test results demonstrated that the market leading PICC had an average of 300% more thrombus accumulation on its surface than the Piper PICC with Quadrasil™ Technology (based on platelet count).8

High Injection Flow Rates

Recommended infusion rate is 5 mL/sec for power injection of contrast media using the 5 French Dual-Lumen Piper PICC.

Easy Identification and Use

In addition to the purple color, each extension leg is clearly labelled “Power-Injectable”. Each extension leg is transparent to allow for visualization of fluid flow.

Easy-to-Read Tags

Each clamp tag is clearly labelled with maximum injection rates and a reminder to users to check the patency and flush the line.

Reverse Taper Design

Helps seal the site of the venotomy, increasing kink resistance and potentially reducing the rate of infiltration.

Available Sizes

Currently the Piper PICC is available in a 5 French Dual Lumen Configuration.

Features and Benefits

Quadrasil™ Technology

Quadrasil™ is not used as a coating, it is a thermoplastic silicone polyurethane co-polymer that exhibits the properties of both urethane and silicone. 



Indications for Use

The 5 FR DL Piper PICC Catheter is indicated for short or long term peripheral access to the central venous system for intravenous therapy, power injection of contrast media, and prolonged exposure to intraluminal solutions containing up to 70% ethanol. The maximum recommended infusion rate is 5mL/sec for power injection of contrast media.

Patent Pending

1. Sanders, J., Pithie, A., Ganly, P., Surgenor, L., Wilson, R., Merriman, E., Loudon, G., Judkins, R., & Chambers, S. (2008). A prospective double-blind randomized trial comparing intraluminal ethanol with heparinized saline for the prevention of catheter-associated bloodstrem infection in immunosuppressed haematology patients. Journal of Antimicrobial Chemotherapy, 62(4), 809-815.
2. Broom, J., Woods, M., Allworth, A., McCarthy, J., Faoagali, J., Macdonald, S., & Pithie, A. (2008). Ethanol lock therapy to treat tunnelled central venous catheter-associated blood stream infections: Results from a prospective trial. Scandinavian Journal of Infectious Diseases, 40, 399-406.
3. Chambers, S. T., Pithie, A., Gallagher, K., Liu, T., Charles, C. J., & Seaward, L. (2007) Treatment of Staphylococcus epidermidis central vascular catheter infection with 70% ethanol locks: Efficacy in a sheep model. Journal of Antimicrobial Chemotherapy, 59(4), 779-782.
4Mouw, E., Chessman, K., Lesher, A., & Tagge, E. (2008). Use of an ethanol lock to prevent catheter-related infections in children with short bowel syndrome. Journal of Pediatric Surgery, 43(6), 1025-1029.
5. Johnston, D. A., Walker, K., Richards, J., & Pennington, C. R. (1992). Ethanol flush for the prevention of catheter occlusion. Clinical Nutrition, 11(2), 97-100.
6. Werlin, S. L., Lausten, T., Jessen, S., Toy, L., Norton, A., Dallman, L., Bender, J., Sabilan L., & Rutkowski, D. (1995). Treatment of central venous catheter occlusions with ethanol and hydrochloric acid. Journal of Parenteral and Enteral Nutrition, 19(5), 416-418.
7. Pennington, C. R., & Pithie, A. D. (1987). Ethanol lock in the management of catheter occlusion. Journal of Parenteral and Enteral Nutrition, 11(5), 507-508.

8. Bench test data on file at Piper Access, LLC

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